Rasmus, in Denmark, has put a 180 km (roughly 110 miles) on his Kangoos with long runs and lots of off road workouts. Here's a link to his video showing where they wore out and what parts he is going to replace.
His evaluation: Don't expect to get more mileage than a pair of running shoes but he still loves running in them and is going to replace the worn parts. Plan on replacing parts more often if you run off road. (Hope I paraphrased you correctly Rasmus ;-)